Cell cycle regulation of Golgi membrane dynamics
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چکیده
منابع مشابه
Monoubiquitination of Syntaxin 5 Regulates Golgi Membrane Dynamics during the Cell Cycle.
The Golgi apparatus undergoes a ubiquitin-dependent disassembly and reassembly process during each cycle of cell division. Here we report the identification of the Golgi t-SNARE syntaxin 5 (Syn5) as the ubiquitinated substrate. Syn5 is monoubiquitinated by the ubiquitin ligase HACE1 in early mitosis and deubiquitinated by the deubiquitinase VCIP135 in late mitosis. Syn5 ubiquitination on lysine...
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ژورنال
عنوان ژورنال: Trends in Cell Biology
سال: 2013
ISSN: 0962-8924
DOI: 10.1016/j.tcb.2013.01.008